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2. Yi Li, Rongxiu Zhu, Jiaozhen Zhang, Xueyi Wu, Tao Shen, Jinchuan Zhou, Yanan Qiao, Yun Gao, and Hongxiang Lou*. Clerodane diterpenoids from the Chinese liverwort Jamesoniella autumnalis and their anti-inflammatory activity. Phytochemistry, 2018, 154: 85–93.

3. Yanan Qiao, Hongbo Zheng, Lin Li, Jiaozhen Zhang, Yi Li, Siwen Li, Rongxiu Zhu,
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4. Jiaozhen Zhang, Yongjie Wang, Rongxiu Zhu, Yi Li, Yuelan Li, Yanan Qiao, Jinchuan Zhoud and Hongxiang Lou*.Cyperane and eudesmane-type sesquiterpenoids from Chinese liverwort and their anti-diabetic nephropathy potential. RSC Advances, 2018, 8: 39091–39097.

5. Yuelan Li, Rongxiu Zhu, Jiaozhen Zhang, Fei Xie, Xiaoning Wang, Ke Xu, Yanan Qiao, Zuntian Zhao, and Hongxiang Lou*. Ophiosphaerellins A-I, Polyketide-Derived Compounds from the Endolichenic Fungus Ophiosphaerella korrae. ACS Omega, 2018, 3: 176-180

6. Ke Xu, Yun Gao, Yuelan Li, Fei Xie, Zuntian Zhao*, and Hongxiang Lou*. Cytotoxic p‑Terphenyls from the Endolichenic Fungus Floricola striata. Journal of Natural Products. 2018, 81: 2041-2049.

7. Jin TY, Li SQ, Jin CR, Shan H, Wang RM, Zhou MX, Li AL, Li LY, Hu SY, Shen T*, Xiang L*. Catecholic Isoquinolines from Portulaca oleracea L. and their anti-inflammatory and β₂-adrenergic receptor agonist activity. Journal of Natural Products. 2018, 81: 768-777.

8. Hu SY, Zheng YN, Ding CB, Hao YW, Cui B, Xiang L*. Isolation and identification of components in the dihydroquercetin-rich extract from larch wood (Larix olgensis Henry). European Journal of Medicinal Plants, 2018, 24(2): 1-8.

9. Yuefang Zhou，Shanshan Wang, Hongxiang Lou, Peihong Fan*. Chemical constituents of hemp (Cannabis sativa L.) seed with potential anti-neuroinflammatory activity. Phytochemistry Letter, 2018, 23,57-61.

10. Yuefang Zhou, Shanshan Wang, Jianbo Ji, Hongxiang Lou, Peihong Fan*. Hemp (Cannabis sativa L.) seed phenylpropionamides composition and effects on memory dysfunction and biomarkers of neuroinflammation induced by lipopolysaccharide in mice. ACS Omega, 2018, 3 (11), 15988–15995

11. Shanshan Wang, Qian Luo, Peihong Fan*. Cannabisin F from Hemp (Cannabis sativa) Seed Suppresses Lipopolysaccharide-Induced Inflammatory Responses in BV2 Microglia as SIRT1 Modulator, International Journal of Molecular Sciences, 2019, 20, 507.

12. Ting Li, Shanshan Wang, Peihong Fan*, Hongxiang Lou. New coumarins and monoterpene galloylglycoside from the stem bark of Sapium baccatum. Fitoterapia, 2019, 134, 435-422.

13. Wenqiang Chang, Jun Liu, Ming Zhang, Hongzhuo Shi, Sha Zheng, Xueyang Jin, Yanhui Gao, Shuqi Wang, Aiguo Ji and Hongxiang Lou*. Efflux pump-mediated resistance to antifungal compounds can be prevented by conjugation with triphenylphosphonium cation. Nature communications, 2018, 9:5102.

14. Sha Zheng, Wenqiang Chang, Ming Zhang, Hongzhuo Shi, and Hongxiang Lou*. Chiloscyphenol a derived from chinese liverworts exerts fungicidal action by eliciting both mitochondrial dysfunction and plasma membrane destruction. Scientific Reports, 2018, 8(1): 326.

15. Ming Zhang, Wenqiang Chang, Hongzhuo Shi, Ying Li, Sha Zheng, Wei Li, and Hongxiang Lou*. Floricolin c elicits intracellular ros accumulation and disrupts mitochondria to exert fungicidal action. FEMS Yeast Research, 2018, 18(1) foy002.

16. Lin Li, Bin Sun, Yun Gao, Huanmin Niu, Huiqing Yuan*, Hongxiang Lou*. STAT3 contributes to lysosomal-mediated cell death in a novel derivative of riccardin D-treated breast cancer cells in association with TFEB. Biochemical Pharmacology. 2018, 150:267-279.

17. Ming-Xing Zhou; Guo-Hui Li; Bin Sun; You-Wei Xu; Ai-Ling Li; Yan-Ru Li; Dong-Mei Ren; Xiao-Ning Wang; Xue-Sen Wen; Hong-Xiang Lou; Tao Shen. Identification of novel Nrf2 activators from Cinnamomum chartophyllum H.W. Li and their potential application of preventing oxidative insults in human lung epithelial cells, Redox Biology, 2018, 14: 154~163

18. Wen-Jing Yang ; Yan-Ru Li ; Hui Gao; Xue-Yi Wu; Xiao-Ling Wang; Xiao-Ning Wang; Lan Xiang; Dong-Mei Ren; Hong-Xiang Lou; Tao Shen. Protective effect of the ethanol extract from Ligusticum chuanxiong rhizome against streptozotocin–induced diabetic nephropathy in mice, Journal of Ethnopharmacology, 2018, 227: 166~175.

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20. Yan-Ru Li ; Chun-Sheng Fu; Wen-Jing Yang; Xiao-Ling Wang; Dan Feng; Xiao-Ning Wang; Dong-Mei Ren; Hong-Xiang Lou; Tao Shen, Investigation of constituents from Cinnamomum camphora (L.) J. Presl and evaluation of theiranti-inflammatory properties in lipopolysaccharidestimulated RAW 264.7 macrophages, Journal of Ethnopharmacology, 2018, 221: 37~47

21. Yan-Ru Li ; Guo-Hui Li; Ming-Xing Zhou; Lan Xiang; Dong-Mei Ren; Hong-Xiang Lou; Xiao-Ning Wang; Tao Shen, Discovery of natural flavonoids as activators of Nrf2-mediated defense system: structure-activity relationship and inhibition of intracellular oxidative insults, Bioorganic & Medicinal Chemistry, 2018, 26: 5140~5150

22. Ai-Ling Li ; Bang-Jiao Chen; Guo-Hui Li; Ming-Xing Zhou; Yan-Ru Li; Dong-Mei Ren; Hong-Xiang Lou; Xiao-Ning Wang, Tao Shen. Physalis alkekengi L. var. franchetii (Mast.) Makino: an ethnomedical, phytochemical and pharmacological review, Journal of Ethnopharmacology, 2018, 210: 260~274

23. Hongbo Zheng, Yifeng Wu, Bin Sun, Chuanle Cheng, Yanan Qiao, Yuehua Jiang, Shengtian Zhao, Zhiyu Xie, Jing Tan, Hongxiang Lou. Discovery of Furyl/Thienyl β-carboline Derivatives as Potent and Selective PDE5 Inhibitors with Excellent Vasorelaxant Effect. Eur. J. Med. Chem. 2018, 158, 767-780.

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30. Na Lu, Jinfeng Ye, Jiansong Cheng, Aniruddha Sasmal, Chang-Cheng Liu, Wenlong Yao, Jun Yan, Naazneen Khan, Wen Yi, Ajit Varki, Hongzhi Cao*. Redox-controlled site-specific α2,6-sialylation. J. Am. Chem. Soc. 2019, 141, 4547−4552.

31. Caicai Meng, Aniruddha Sasmal, Yan Zhang, Tian Gao, Chang-Cheng Liu, Naazneen Khan,Ajit Varki, Fengshan Wang,* Hongzhi Cao*. Chemoenzymatic assembly of mammalian O-mannose glycans. Angew. Chem. Int. Ed. 2018, 57, 9003-9007.

32. Yangyang Xu, Yueyuan Fan, Jinfeng Ye, Faxing Wang, Quandeng Nie, Li Wang, Peng George Wang*, Hongzhi Cao*, and Jiansong Cheng*. Successfully engineering a bacterial sialyltransferase for regioselective α2,6-sialylation. ACS Catal. 2018, 8, 7222-7227.

33. Tong Li, Tianlu Li, Tongxiao Cui, Yajing Sun, Fengshan Wang, Hongzhi Cao, Richard R. Schmidt*, Peng Peng* Regioselective One-Pot Benzoylation of Triol and Tetraol Arrays in Carbohydrates. Org. Lett. 2018, 20, 3862-3865.

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35. Wang T-T, Zhu C-Y, Zheng S, Meng C-C, Wang T-T, Meng D-H, Li Y-J, Zhu H-M, Wang F-S, Sheng J-Z* (2018) Identification and characterization of a chondroitin synthase from Avibacterium paragallinarum. Appl Microbiol Biotechnol 102:4785–4797 . doi: 10.1007/s00253-018-8926-4

36. Li Y-J, Yin F-X, Zhang X-K, Yu J, Zheng S, Song X-L, Wang F-S, Sheng J-Z* (2018) Characterization of heparan sulfate N-deacetylase/N-sulfotransferase isoform 4 using synthetic oligosaccharide substrates. Biochimica et Biophysica Acta (BBA) - General Subjects 1862:547–556.

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41. Yiming Jin, Pingli Li, Fengshan Wang*.b-glucans as potential immunoadjuvants: A review on the adjuvanticity, structure-activity relationship and receptor recognition properties. Vaccine, 2018, 36: 5235-5244.

42. Feng Sun, Yang Yu, Zhifang Yang, Zhendong Wang, Yan Li, Fengshan Wang, Haining Tan*. Hyaluronic acid-endostatin2-alft1 (HA-ES2-AF) nanoparticle-like conjugate for the target treatment of diseases. J Control Release, 2018, 288:1-13.

43. Feng Sun, Zhendong Wang, Zhifang Yang, Yan Li, Huifei Cui, Chunhui Liu, Dezong Gao, Fengshan Wang, Haining Tan*. Characterization, bioactivity and pharmacokinetic study of a novel carbohydrate-peptide polymer: glycol-split heparin-endostatin2 (GSHP-ES2). Carbohydrate Polymers, 2019, 207: 79-90.

44. Qixin Chen, Chengzhi Jin, Xintian Shao, Ruilin Guan, Zhiqi Tian, Chenran Wang, Fei Liu,Peixue Ling, Jun-Lin Guan, Liangnian Ji, Fengshan Wang*, Hui Chao*, Jiajie Diao*. Super-Resolution Tracking of Mitochondrial Dynamics with An Iridium(III) Luminophore. Small, 2018, 14: 1802166.

45. Xintian Shao, Qixin Chen, Xixi Dou, Lei Chen, Jixu Wu, Wei Zhang, Huarong Shao, Peixue Ling*, Fei Liu*, Fengshan Wang*. Lower range of molecular weight of xanthan gum inhibits cartilage matrix destruction via intrinsic bax-mitochondria cytochrome c-caspase pathway. Carbohydrate Polymers, 2018, 198: 354–363.

46. Fuyan Liu, Xiaofeng Zhang, Yuqiu Li, Hui Gao, Peixue Ling*, Xiaoyan Li, Qixin Chen, Aibin Ma, Huarong Shao, Mei Li, Fengshan Wang*. Simultaneous Screening and Determination of Eight Tetracycline Antibiotics Illegally Adulterated in Herbal Preparations Using HPLC-DAD Combined with LC-MS-MS. Chromatographia, 2018, 81 (36):303-314.

47. Zhang, Jian; Poongavanam, Vasanthanathan; Kang, Dongwei; Bertagnin, Chiara; Lu, Huamei; Kong, Xiujie; Ju, Han; Lu, Xueyi; Gao, Ping; Tian, Ye; Jia, Haiyong; Desta, Samuel; Ding, Xiao; Sun, Lin; Fang, Zengjun; Huang, Boshi; Liang, Xuewu; Jia, Ruifang; Ma, Xiuli; Xu, Wenfang; Murugan, Natarajan Arul; Loregian, Arianna; Huang, Bing*; Zhan, Peng*; Liu, Xinyong*. Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant. J Med Chem. 2018 Jul 26;61(14):6379-97

48. Zhang, Jian; Murugan, Natarajan Arul; Tian, Ye; Bertagnin, Chiara; Fang, Zengjun; Kang, Dongwei; Kong, Xiujie; Jia, Haiyong; Sun, Zhuosen; Jia, Ruifang; Gao, Ping; Poongayanam, Vasanthanathan; Loregian, Arianna; Xu, Wenfang; Ma, Xiuli; Ding, Xiao; Huang, Bing*; Zhan, Peng*; Liu, Xinyong*. Structure-Based Optimization of N-Substituted Oseltamivir Derivatives as Potent Anti-Influenza A Virus Agents with Significantly Improved Potency against Oseltamivir-Resistant N1-H274Y Variant. J Med Chem. 2018 Nov 21;61(22):9976-99

49. Yang, Yang; Kang, Dongwei; Nguyen, Laura A.; Smithline, Zachary B.; Pannecouque, Christophe; Zhan, Peng*; Liu, Xinyong*; Steitz, Thomas A.*. Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2-d] pyrimidine non-nucleoside inhibitors. Elife. 2018 Jul 25;7. pii: e36340

50. Wu, Gaochan; Zalloum, Waleed A.; Meuser, Megan E.; Jing, Lanlan; Kang, Dongwei; Chen, Chin-Ho; Tian, Ye; Zhang, Fangfang; Cocklin, Simon*; Lee, Kuo-Hsiung*; Liu, Xinyong*; Zhan, Peng*. Discovery of phenylalanine derivatives as potent HIV-1 capsid inhibitors from click chemistry-based compound library. Eur J Med Chem. 2018 Oct 5;158:478-92

51. Tian, Ye; Liu, Zhaoqiang; Liu, Jinghan; Huang, Boshi; Kang, Dongwei; Zhang, Heng; De Clercq, Erik; Daelemans, Dirk; Pannecouque, Christophe; Lee, Kuo-Hsiung; Chen, Chin-Ho; Zhan, Peng*; Liu, Xinyong*. Targeting the entrance channel of NNIBP: Discovery of diarylnicotinamide 1,4-disubstituted 1,2,3-triazoles as novel HIV-1 NNRTIs with high potency against wild-type and E138K mutant virus. Eur J Med Chem. 2018 May 10;151:339-50

52. Sun, Lin; Gao, Ping; Dong, Guanyu; Zhang, Xujie; Cheng, Xiqiang; Ding, Xiao; Wang, Xueshun; Daelemans, Dirk; De Clercq, Erik; Pannecouque, Christophe*; Menendez-Arias, Luis*; Zhan, Peng*; Liu, Xinyong*. 5-Hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives as novel dual inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H and integrase. Eur J Med Chem. 2018 Jun 18;155:714-24

53. Ju, Han; Zhang, Jian; Sun, Zhuose; Huang, Zheng; Qi, Wenbao; Huang, Bing; Zhan, Peng*; Liu, Xinyong*. Discovery of C-1 modified oseltamivir derivatives as potent influenza neuraminidase inhibitors. Eur J Med Chem. 2018 Feb 25;146:220-31

54. Huo, Zhipeng; Zhang, Heng; Kang, Dongwei; Zhou, Zhongxia; Wu, Gaochan; Desta, Samuel; Zuo, Xiaofang; Wang, Zhao; Jing, Lanlan; Ding, Xiao; Daelemans, Dirk; De Clercq, Erik; Pannecouque, Christophe; Zhan, Peng*; Liu, Xinyong*. Discovery of Novel Diarylpyrimidine Derivatives as Potent HIV-1 NNRTIs Targeting the "NNRTI Adjacent" Binding Site. ACS Med Chem Lett. 2018 Feb 27;9(4):334-8

55. Kang, Dongwei; Wang, Zhao; Zhang, Heng; Wu, Gaochan; Zhao, Tong; Zhou, Zhongxia;Huo, Zhipeng; Huang, Boshi; Feng, Da; Ding, Xiao; Zhang, Jian; (Zuo, Xiaofang; Jing, Lanlan; Luo, Wei; Guma, Samuel; Daelemans, Dirk; De Clercq, Erik; Pannecouque, Christophe; Zhan, Peng*; Liu, Xinyong*. Further Exploring Solvent-Exposed Tolerant Regions of Allosteric Binding Pocket for Novel HIV-1 NNRTIs Discovery. ACS Med Chem Lett. 2018 Mar 1;9(4):370-5

56. Lu, Xueyi; Yang, Jiapei; Kang, Dongwei; Gao, Ping; Daelemans, Dirk; De Clercq, Erik; Pannecouque, Christoph; Zhan, Peng; Liu, Xinyong*. The discovery of novel diarylpyri(mi) dine derivatives with high level activity against a wide variety of HIV-1 strains as well as against HIV-2. Bioorg Med Chem. 2018 May 1;26(8):2051-60

57. Huang, Boshi; Liu, Xinhao; Tian, Ye; Kang, Dongwei; Zhou, Zhongxia; Daelemans, Dirk; De Clercq, Erik; Pannecouque, Christophe; Zhan, Peng*; Liu, Xinyong*. First discovery of a potential carbonate prodrug of NNRTI drug candidate RDEA427 with submicromolar inhibitory activity against HIV-1 K103N/Y181C double mutant strain. Bioorg Med Chem Lett. 2018 May 1;28(8):1348-51

58. Wang, Zhao; Kang, Dongwei; Chen, Meng; Wu, Gaochan; Feng, Da; Zhao, Tong; Zhou, Zhongxia; Huo, Zhipeng; Jing, Lanlan; Zuo, Xiaofang; Daelemans, Dirk; De Clercq, Erik; Pannecouque, Christophe; Zhan, Peng*; Liu, Xinyong*. Design, synthesis, and antiviral evaluation of novel hydrazone-substituted thiophene[3,2-d]pyrimidine derivatives as potent human immunodeficiency virus-1 inhibitors. Chem Biol Drug Des. 2018 Dec;92(6):2009-21

59. Zhou, Zhongxia; Liu, Tao; Kang, Dongwei; Huo, Zhipeng; Wu, Gaochan; Daelemans, Dirk; De Clercq, Erik; Pannecouque, Christophe; Zhan, Peng*; Liu, Xinyong*. Discovery of novel diarylpyrimidines as potent HIV-1 NNRTIs by investigating the chemical space of a less explored "hydrophobic channel". Org Biomol Chem. 2018 Feb 7;16(6):1014-28

60. Feng, Da; Wei, Fenju; Wang, Zhao; Kang, Dongwei*; Zhan, Peng*; Liu, Xinyong*. Development of a practical synthesis of etravirine via a microwave-promoted amination. Chem Cent J. 2018 Dec 20;12(1):144

61. Wang, Xueshun; Gao, Ping; Menendez-Arias, Luis; Liu, Xinyong*; Zhan, Peng*. Update on Recent Developments in Small Molecular HIV-1 RNase H Inhibitors (2013-2016): Opportunities and Challenges. Curr Med Chem. 2018;25(14):1682-702

62. Zou, Jinmi; Gao, Ping; Hao, Xia; Xu, Haoran; Zhan, Peng; Liu, Xinyong*. Recent progress in the structural modification and pharmacological activities of ligustrazine derivatives. Eur J Med Chem. 2018 Mar 10;147:150-62

63. Zhou, Zhongxia; Liu, Tao; Zhang, Jian; Zhan, Peng*; Liu, Xinyong*. Influenza A virus polymerase: an attractive target for next-generation anti-influenza therapeutics. Drug Discov Today. 2018 Mar;23(3):503-18

64. Zuo, Xiaofang; Huo, Zhipeng; Kang, Dongwei; Wu, Gaochan; Zhou, Zhongxia; Liu, Xinyong*; Zhan, Peng*. Current insights into anti-HIV drug discovery and development: a review of recent patent literature (2014-2017). Expert Opin Ther Pat. 2018 Apr;28(4):299-316

65. Liu, Hu; Tian, Ye; Lee, Kyungae; Krishnan, Pranav; Wang, May Kwang-Mei; Whelan, Sean; Mevers, Emily; Soloveva, Veronica; Dedic, Benjamin; Liu, Xinyong; Cunningham, James M*. Identification of potent Ebola virus entry inhibitors with suitable properties for in vivo studies. J Med Chem. 2018 Jul 3;61(14):6293-307

66. Zhongyue Li, Deyu Zhu, Yuemao Shen* (2018). Discovery of novel bioactive natural products driven by genome mining. Drug Discov. Ther. 12, 318–328.

67. Yuemao Shen*, Duozhi Chen (2018). An explorer of chemical biology of plant natural products in Southwest China, Xiaojiang Hao. Nat. Prod. Bioprospect. 8, 217–226.

68. Yaoyao Li, Haoxin Wang, Yan Liu, Yujie Jiao, Shanren Li, Yuemao Shen*, Liangcheng Du* (2018). Biosynthesis of the polycyclic system in the antifungal HSAF and analogues from Lysobacter enzymogenes. Angew. Chem. Int. Ed. 57, 6221–6225.

69. Xingkang Wu, Zhenyu Li, Yuemao Shen* (2018). The small molecule CS1 inhibits mitosis and sister chromatid resolution in HeLa cells. BBA – Gen. Subjects 1862, 1134–1147.

70. Xingkang Wu, Yuemao Shen* (2018). PMN inhibits colorectal cancer cells through inducing mitotic arrest and p53-dependent apoptosis via the inhibition of tubulin polymerization. Biochem. Biophys. Res. Commun. 499 (4), 927–933.

71. Chuanpeng Liang, Xingkang Wu, Zhenyu Li, Jing Zhu, Chunhua Lu, Yuemao Shen* (2018). Design, synthesis and pharmacological evaluation of N-(5-chloro-2,4-dihydroxybenzoyl)-(R)-N-arylmethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxamides as potent Hsp90 inhibitors. Eur. J. Med. Chem. 143, 85–96.

72. Wei Xie, Wei Zhang, Mingwei Sun, Chunhua Lu, Yuemao Shen* (2018). Deacetylmycoepoxydiene is an agonist of Rac1, and simultaneously induces autophagy and apoptosis. Appl. Microbiol. Biotechnol. 102, 5965–5975.

73. Xiaomei Li, Xingkang Wu, Jing Zhu, Yuemao Shen* (2018). Amexanthomycins A–J, pentangular polyphenols produced by Amycolatopsis mediterranei S699∆rifA. Appl. Microbiol. Biotechnol. 102, 689–702.

74. Tianhong Li, Dongdong Zhang, Thaung Naing Oo, Myint Myint San, Aye Mya Mon, Pyae Phyo Hein, Yuehu Wang, Chunhua Lu*, Xuefei Yang* (2018). Investigation on the antibacterial and anti-T3SS activity of traditional Myanmar medicinal plants. Evidence-based Complementary and Alternative Medicine 2018, 1–13.

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76. Yan Liu, Haoxin Wang, Rentai Song, Jining Chen, Tianhong Li, Yaoyao Li*, Liangcheng Du, Yuemao Shen (2018).Targeted discovery and combinatorial biosynthesis of polycyclic tetramate macrolactam combamides A-E. Org Lett. 20, 3504–3508.

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87. X. Li, Y.K. Peterson, E.S. Inks, R.A. Himes, J. Li, Y. Zhang*, X. Kong, C.J. Chou, Class I HDAC Inhibitors Display Different Antitumor Mechanism in Leukemia and Prostatic Cancer Cells Depending on Their p53 Status, J. Med. Chem., 61 (2018) 2589-2603.

88. J. Zang, X. Liang, Y. Huang, Y. Jia, X. Li, W. Xu, C.J. Chou, Y. Zhang*, Discovery of Novel Pazopanib-Based HDAC and VEGFR Dual Inhibitors Targeting Cancer Epigenetics and Angiogenesis Simultaneously, J. Med. Chem., 61 (2018) 5304-5322.

89. C. Zhao, J. Zang, Q.g. Ding, E.S. Inks, W. Xu, C.J. Chou, Y. Zhang*, Discovery of meta-sulfamoyl N-hydroxybenzamides as HDAC8 selective inhibitors, Eur. J. Med. Chem., 150 (2018) 282-291.

90. J. Cao, J. Zang, C. Ma, X. Li, J. Hou, J. Li, Y. Huang, W. Xu, B. Wang, Y. Zhang*, Design, Synthesis, and Biological Evaluation of Pyrazoline-Based Hydroxamic Acid Derivatives as Aminopeptidase N (APN) Inhibitors, ChemMedChem, 13 (2018) 431-436.

91. J. Cao, C. Ma, J. Zang, S. Gao, Q. Gao, X. Kong, Y. Yan, X. Liang, Q.g. Ding, C. Zhao, B. Wang, W. Xu, Y. Zhang*, Novel leucine ureido derivatives as aminopeptidase N inhibitors using click chemistry, Biorg. Med. Chem., 26 (2018) 3145-3157.

92. Fansheng Ran, Yang Liu, Daoguang Zhang, Meixia Liu, GuisenZhao*. Discovery of novel pyrazole derivatives as potential anticancer agents in MCL. Bioorganic & Medicinal Chemistry Letters, 2019, 29(9): 1060-1064.

93. Junze Dong, Jingya Zhang, Zilu Li, Solomon Asnake, Daoguang Zhang, PerErik Olsson*, Guisen Zhao*. Design, synthesis, and biological evaluation of 2-(5-methyl-1H-pyrazol-1-yl) acetamide derivatives as androgen receptor antagonists. Medicinal Chemistry Research, 2019, 28(3), 380-386.

94. Daoguang Zhang, Solomon Asnake, Jingya Zhang, Per-Erik Olsson*, Guisen Zhao*. Discovery of novel 5-methyl-1H-pyrazole derivatives as potential anti-prostate cancer agents: design, synthesis, molecular modeling and biological evaluation. Chemical Biology & Drug Design, 2018, 91(6): 1113-1124.

95. Daoguang Zhang, Dongdong Tong, Dezhi Yang, Jing Sun, Fenghe Zhang*, Guisen Zhao*. Design, synthesis and biological evaluation of AKT inhibitors bearing a piperidin-4-yl appendant. MedChemComm, 2018, 9(8): 1340-1350.

96. Zhen Zhang, Daoguang Zhang, Yang Liu, Dezhi Yang, Fansheng Ran, Michael L. Wang, Guisen Zhao*. Targeting Bruton's tyrosine kinase for the treatment of B cell associated malignancies and autoimmune diseases: Preclinical and clinical developments of small molecule inhibitors. Archiv der Pharmazie, 2018, 351(7): e1700369.

97. Jiang T, Zhu P, Du L and Li MY.^* Identification of AI-2 Quorum Sensing Inhibitors in Vibrio harveyi Through Structure-Based Virtual Screening. Methods Mol. Biol. 2018, 1673, 353-362.

98. Lin Y, Gao Y., Ma Z., Jiang T., Zhou X., Li Z., Qin X., Huang Y., Du L. and Li MY.^* Bioluminescence probe for γ-glutamyl transpeptidase detection in vivo. Bioorg. Med. Chem. 2018, 26, 134-40.

99. Yang X, Li Z, Jiang T, Du L and Li MY.^* A coelenterazine-type bioluminescent probe for nitroreductase imaging, Org. Biomol. Chem. 2018, 16, 146-51.

100. Tang C, Gao Y, Liu T, Lin Y, Zhang X, Zhang C, Li X, Zhang T, Du L and Li MY.^* Bioluminescent probe for detecting endogenous hypochlorite in living mice, Org. Biomol. Chem. 2018, 16, 645-51.

101. Zhang Y, Ma L, Tang C, Pan S, Shi D, Wang S, Li MY^* and Guo Y. A highly sensitive and rapidly responding fluorescent probe based on a rhodol fluorophore for imaging endogenous hypochlorite in living mice, J. Mater. Chem. B. 2018, 6, 725-31.

102. Li X and Li MY.^* Optical probes, theranostics and optogenetics shed light on zebrafish (Danio rerio), Anal. Method. 2018, 10, 818-31.

103. Tang C, Jin L, Lin Y, Su J, Sun Y, Liu P, Li Q, Wang G, Zhang Z, Du L and Li MY.^* Aminoluciferin 4-hydroxyphenyl amide enables bioluminescence detection of endogenous tyrosinase. Org. Biomol. Chem. 2018, 16, 9197-9203.

104. Zhang C, Cheng L, Dong G, Han G, Yang X, Tang C, Li X, Zhou Y, Du L and Li MY.^* Novel photoactivatable substrates for Renilla luciferase imaging in vitro and in vivo. Org. Biomol. Chem. 2018, 16, 4789-4792.

105. Ke B, Chen H, Ma L, Zingales S, Gong D, Hu D, Du L and Li MY.^* Visualization of mercury(ii) accumulation in vivo using bioluminescence imaging with a highly selective probe. Org. Biomol. Chem. 2018, 16, 2388-2392.

106. Zhang C, Yuan M, Han G, Gao Y, Tang C, Li X, Du L and Li MY.^*Novel caged luciferin derivatives can prolong bioluminescence imaging in vitro and in vivo. RSC Adv. 2018, 8, 19596-19599.

107. Lin YX, Gao YQ, Ma Z, Li ZZ, Tang CC, Qin XJ, Zhang Z, Wang GK, Du LP and Li MY^*. Bioluminescent Probe for Detection of Starvation-Induced Pantetheinase Upregulation. Anal. Chem. 2018, 90, 9545-50.

108. Ke B, Ma L, Kang T, He W, Gou X, Gong D, Du LP and Li MY^*. In Vivo Bioluminescence Imaging of Cobalt Accumulation in a Mouse Model. Anal. Chem. 2018, 90:4946-4950.

109. Chen-Chen Ma, Cheng-Mei Zhang, Long-Qian Tang, Zhao-Peng Liu*, Discovery of novel quinazolinone derivatives as high potent and selective PI3Kδ and PI3Kδ/γ inhibitors. Eur. J. Med. Chem. 2018, 151, 9–17.

110. Hu W, Huang X, Wu J, Yang L, Zheng Y*, Shen Y, Li Z, Li X*. Discovery of novel topoisomerase II inhibitors by medicinal chemistry approaches. J. Med. Chem. 2018, 61(20), 8947-8980.

111. 2）Du Z, Sun J, Bader CA, Brooks DA, Li M, Li X*, Plush SE*. Synthesis, photophysical and cellular characterization of folate and methotrexate labelled luminescent lanthanide complexes. J. Inorg. Biochem. 2018, 178, 32-42.

112. Li X*. Gelatinase inhibitors (2011-2017): a patent review. Expert Opinion on Therapeutic Patents. 2018, 28(1), 31-46.

113. Quinoxalinone as a privileged platform in drug development. Shi L, Hu W, Wu J, Zhou H, Li X*. Mini-Rev Med Chem. 2018, 18(5), 392-413.

114. Roscoe I, Parker M, Dong D, Li X, Li Z*. Human serum albumin and the p53-derived peptide fusion protein promotes cytotoxicity irrespective of p53 status in cancer cells. Mol Pharm. 2018, 15, 5046-5057.